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Company ReportsDay One Biopharmaceuticals

Day One Biopharmaceuticals(DAWN)

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Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

,

,

healthy volunteers/patients

,

acquired immunodeficiency syndrome

,

,

,

,

,

,

myelodysplastic syndromes

,

myeloid leukemia acute

,

precursor cell lymphoblastic leukemia-lymphoma

,

bcr-abl positive chronic myelogenous leukemia

,

myeloid leukemia

,

multiple myeloma

,

biphenotypic leukemia acute

,

,

,

,

myeloid leukemia chronic-phase

,

refractory anemia

,

colorectal neoplasms

,

pancreatic neoplasms

,

non-small-cell lung carcinoma

,

,

,

lymphoid leukemia

,

hematologic neoplasms

,

myeloid leukemia accelerated phase

,

refractory anemia with excess of blasts

,

non-hodgkin lymphoma

,

primary myelofibrosis

,

,

b-cell chronic lymphocytic leukemia

,

b-cell lymphoma marginal zone

,

prolymphocytic leukemia

,

follicular lymphoma

,

mantle-cell lymphoma

,

waldenstrom macroglobulinemia

,

burkitt lymphoma

,

,

,

urinary bladder neoplasms

,

,

papillary thyroid cancer

,

acinar cell carcinoma

,

craniopharyngioma

,

langerhans-cell histiocytosis

,

hairy cell leukemia

,

brain neoplasms

,

diffuse intrinsic pontine glioma

brain neoplasms

,

nutritional status

,

,

pneumococcal pneumonia

,

,

male breast neoplasms

,

respiratory tract infections

,

embryo transfer

,

,

,

,

postpartum hemorrhage

,

inflammatory bowel diseases

,

,

tendon injuries

,

,

community-acquired infections

,

haemophilus influenzae

,

streptococcus pneumoniae

,

prostatic neoplasms

,

,

energy metabolism

,

ovarian epithelial carcinoma

,

head and neck neoplasms

,

stomach neoplasms

,

gastrointestinal neoplasms

,

digestive system neoplasms

,

neoplasms by site

,

non-small-cell lung carcinoma

,

,

falciparum malaria

,

,

renal cell carcinoma

,

colorectal neoplasms

,

,

healthy volunteers/patients

,

,

,

multiple myeloma

,

pancreatic neoplasms

,

uterine cervical neoplasms

,

squamous cell carcinoma of head and neck

,

,

type 1 diabetes mellitus

,

sickle cell anemia

,

sjogren's syndrome

,

,

,

respiration disorders

,

chronic hepatitis b

,

endometrial neoplasms

,

plasma cell neoplasms

,

malignant mesothelioma

,

cutaneous malignant melanoma

,

streptococcus agalactiae

,

follicular lymphoma

,

microsatellite repeats

,

small cell lung carcinoma

,

macular degeneration

,

b-cell lymphoma

,

,

,

,

respiratory tract diseases

,

,

focal segmental glomerulosclerosis

,

cytomegalovirus infections

,

membranous glomerulonephritis

,

nephrotic syndrome

,

endometrioid carcinoma

,

fallopian tube neoplasms

,

systemic scleroderma

,

,

granulomatosis with polyangiitis

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

precursor cell lymphoblastic leukemia-lymphoma

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

,

,

,

,

kidney transplantation

,

,

,

,

b-cell chronic lymphocytic leukemia

,

beta-thalassemia

,

,

sickle cell trait

,

,

,

clear cell adenocarcinoma

,

large cell carcinoma

,

vaginal neoplasms

,

vulvar neoplasms

,

,

breast neoplasms

,

,

rheumatoid arthritis

,

ovarian neoplasms

,

haemophilus influenzae type b

,

haemophilus infections

,

,

chronic renal insufficiency

,

,

neisseria meningitidis

,

respiratory syncytial virus infections

,

streptococcal infections

,

,

muscle spasticity

,

kidney diseases

,

postmenopausal osteoporosis

,

non-hodgkin lymphoma

,

,

human influenza

,

,

,

insulin resistance

,

pneumococcal infections

,

thrombocytopenic purpura idiopathic

,

inflammatory breast neoplasms

,

ductal carcinoma breast

,

,

,

,

abdominal obesity

,

,

,

,

chronic kidney failure

,

,

large b-cell lymphoma diffuse

,

,

renal insufficiency

,

systemic lupus erythematosus

,

myocardial infarction

,

st elevation myocardial infarction

,

acute coronary syndrome

,

,

,

left ventricular hypertrophy

,

rotavirus infections

,

,

,

meningococcal infections

,

,

mucinous adenocarcinoma

,

,

meningococcal meningitis

,

,

thrombocytopenia

,

respiratory syncytial viruses

,

type 2 diabetes mellitus

,

diabetes mellitus

,

,

,

,

,

chronic obstructive pulmonary disease

,

acquired immunodeficiency syndrome

,

,

,

,

,

metabolic bone diseases

,

obstructive lung diseases

,

pulmonary eosinophilia

,

,

,

chronic bronchitis

,

,

chronic disease

,

growth and development

,

,

,

immunologic tests

,

,

alzheimer disease

,

cardiovascular diseases

,

wasting syndrome

,

,

lipid metabolism

,

resistance training

,

,

,

major depressive disorder

,

depressive disorder

,

,

allergic rhinitis seasonal

,

clostridioides difficile

Globulin, immune

hematologic neoplasms

,

,

transitional cell carcinoma

,

pancreatic ductal carcinoma

,

neurofibromatosis 1

,

hereditary sensory and autonomic neuropathies

,

multiple sclerosis

,

thyroid neoplasms

,

,

myelodysplastic syndromes

,

myeloproliferative disorders

,

b-cell chronic lymphocytic leukemia

,

small cell lung carcinoma

,

t-cell lymphoma cutaneous

,

,

merkel cell carcinoma

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

retinal detachment

,

wet macular degeneration

,

polypoidal choroidal vasculopathy

,

atopic dermatitis

,

pancreatic neoplasms

,

esophageal squamous cell carcinoma

,

adenocarcinoma of lung

,

,

,

head and neck neoplasms

,

liver neoplasms

,

hepatocellular carcinoma

,

ovarian neoplasms

,

urologic neoplasms

,

hodgkin disease

,

burkitt lymphoma

,

triple negative breast neoplasms

,

prostatic neoplasms

,

,

,

esophageal neoplasms

,

,

,

vascular diseases

,

myeloid leukemia

,

urologic diseases

,

t-cell lymphoma

,

t-cell lymphoma peripheral

,

mycosis fungoides

,

macular degeneration

,

ovarian epithelial carcinoma

,

brain neoplasms

,

endometrial neoplasms

,

invasive hydatidiform mole

,

,

diabetes mellitus

,

diabetic retinopathy

,

disease progression

,

male breast neoplasms

,

dermatomyositis

,

hypercholesterolemia

,

interstitial cystitis

,

,

,

postherpetic neuralgia

,

immune system diseases

,

blood protein disorders

,

lymphoproliferative disorders

,

neoplasms by histologic type

,

hemostatic disorders

,

paraproteinemias

,

immunoproliferative disorders

,

hemorrhagic disorders

,

waldenstrom macroglobulinemia

,

kidney diseases

,

glandular and epithelial neoplasms

,

,

urinary bladder diseases

,

monocytic leukemia acute

,

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

hematopoietic stem cell transplantation

,

discoid lupus erythematosus

,

cutaneous lupus erythematosus

,

,

chronic hepatitis b

,

persistent infection

,

fallopian tube neoplasms

,

peritoneal neoplasms

,

neurofibromatoses

,

,

cytokine release syndrome

,

systemic scleroderma

,

,

diffuse scleroderma

,

meningeal neoplasms

,

colorectal neoplasms

,

breast neoplasms

,

non-small-cell lung carcinoma

,

renal cell carcinoma

,

myeloid leukemia acute

,

,

squamous cell carcinoma of head and neck

,

plasma cell neoplasms

,

alzheimer disease

,

,

,

colonic neoplasms

,

,

non-hodgkin lymphoma

,

large b-cell lymphoma diffuse

,

neoplasm metastasis

,

urinary bladder neoplasms

,

b-cell lymphoma

,

kidney neoplasms

,

knee osteoarthritis

,

,

rectal neoplasms

,

follicular lymphoma

,

juvenile arthritis

,

squamous cell carcinoma

,

,

rectal diseases

,

squamous cell neoplasms

,

meningococcal infections

,

non-muscle invasive bladder neoplasms

,

aplastic anemia

,

gastrointestinal neoplasms

,

digestive system neoplasms

,

gastrointestinal diseases

,

intestinal neoplasms

,

digestive system diseases

,

colonic diseases

,

intestinal diseases

,

urogenital neoplasms

,

hip osteoarthritis

,

,

hematologic diseases

,

cardiovascular diseases

,

neoplasms by site

,

stomach neoplasms

,

,

,

bronchiolitis obliterans syndrome

,

lymphoid leukemia

,

adenosquamous carcinoma

,

large cell carcinoma

,

,

,

antibody formation

,

neoadjuvant therapy

,

kidney transplantation

,

residual neoplasm

,

small cell carcinoma

,

rheumatoid arthritis

,

,

multiple myeloma

,

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

healthy volunteers/patients

,

ankylosing spondylitis

,

psoriatic arthritis

,

,

ulcerative colitis

,

precursor b-cell lymphoblastic leukemia-lymphoma

,

tick-borne encephalitis

,

,

pharmacokinetics

,

,

spondylarthritis

,

axial spondyloarthritis

,

pneumococcal infections

,

,

non-radiographic axial spondyloarthritis

,

electrocardiography

,

,

rheumatic fever

,

papulosquamous skin diseases

,

inflammatory bowel diseases

,

spondylarthropathies

,

rheumatic diseases

,

,

meningococcal meningitis

,

,

vaccine immunogenicity

,

,

Histone-arginine methyltransferase carm1

multiple myeloma

,

myeloid leukemia

,

hypercholesterolemia

,

atherosclerosis

,

plasma cell neoplasms

,

gastrointestinal neoplasms

,

intestinal neoplasms

,

,

b-cell lymphoma

,

hematologic neoplasms

,

non-hodgkin lymphoma

,

bcr-abl positive chronic myelogenous leukemia

,

hodgkin disease

,

,

alzheimer disease

,

myeloid leukemia acute

,

b-cell chronic lymphocytic leukemia

,

follicular lymphoma

,

large b-cell lymphoma diffuse

,

b-cell leukemia

,

,

hepatocellular carcinoma

,

liver neoplasms

,

,

healthy volunteers/patients

,

,

,

colorectal neoplasms

,

chronic hepatitis

,

,

,

pancreatic neoplasms

,

squamous cell carcinoma of head and neck

,

myeloid leukemia chronic-phase

,

bronchiolitis obliterans syndrome

,

,

hepatitis b virus

,

,

ovarian neoplasms

,

fallopian tube neoplasms

,

clear cell adenocarcinoma

,

uveal neoplasms

,

cutaneous malignant melanoma

,

,

diabetic neuropathies

,

,

idiopathic pulmonary fibrosis

,

pulmonary fibrosis

,

,

,

depressive disorder

,

,

postherpetic neuralgia

,

interstitial lung diseases

,

common variable immunodeficiency

,

coronary disease

,

coronary artery disease

,

myocardial ischemia

,

rectal neoplasms

,

urinary bladder neoplasms

,

head and neck neoplasms

,

squamous cell carcinoma

,

pancreatic ductal carcinoma

,

brain neoplasms

,

,

triple negative breast neoplasms

,

,

,

,

prostatic neoplasms

,

non-small-cell lung carcinoma

,

breast neoplasms

,

chronic hepatitis c

,

diabetes mellitus

,

small cell lung carcinoma

,

renal cell carcinoma

,

systemic lupus erythematosus

,

,

,

neoplasm metastasis

,

,

connective tissue diseases

,

immune system diseases

,

autoimmune diseases

,

venous thrombosis

,

pulmonary embolism

,

,

developmental disabilities

,

autism spectrum disorder

,

pervasive child development disorders

,

,

,

type 2 diabetes mellitus

,

rheumatoid arthritis

,

,

,

chronic hepatitis b

,

atrial fibrillation

,

communicable diseases

,

,

systemic scleroderma

,

juvenile arthritis

,

psoriatic arthritis

,

ankylosing spondylitis

,

sjogren's syndrome

,

undifferentiated connective tissue diseases

,

,

,

mixed connective tissue disease

multiple myeloma

,

hypercholesterolemia

,

atherosclerosis

,

plasma cell neoplasms

,

acquired immunodeficiency syndrome

,

,

gastrointestinal neoplasms

,

intestinal neoplasms

,

,

alzheimer disease

,

myeloid leukemia acute

,

b-cell chronic lymphocytic leukemia

,

follicular lymphoma

,

large b-cell lymphoma diffuse

,

myeloid leukemia

,

b-cell leukemia

,

,

healthy volunteers/patients

,

,

,

prostatic neoplasms

,

colorectal neoplasms

,

,

chronic hepatitis

,

,

squamous cell carcinoma of head and neck

,

myeloid leukemia chronic-phase

,

bronchiolitis obliterans syndrome

,

,

,

hepatitis b virus

,

,

ovarian neoplasms

,

fallopian tube neoplasms

,

clear cell adenocarcinoma

,

diabetic neuropathies

,

,

idiopathic pulmonary fibrosis

,

pulmonary fibrosis

,

,

,

depressive disorder

,

,

postherpetic neuralgia

,

interstitial lung diseases

,

common variable immunodeficiency

,

coronary disease

,

coronary artery disease

,

myocardial ischemia

,

urinary bladder neoplasms

,

head and neck neoplasms

,

squamous cell carcinoma

,

pancreatic ductal carcinoma

,

pancreatic neoplasms

,

brain neoplasms

,

,

triple negative breast neoplasms

,

,

,

,

,

diabetes mellitus

,

,

breast neoplasms

,

non-small-cell lung carcinoma

,

,

renal cell carcinoma

,

chronic hepatitis c

,

small cell lung carcinoma

,

systemic lupus erythematosus

,

,

,

neoplasm metastasis

,

,

connective tissue diseases

,

immune system diseases

,

autoimmune diseases

,

venous thrombosis

,

pulmonary embolism

,

,

developmental disabilities

,

autism spectrum disorder

,

pervasive child development disorders

,

type 2 diabetes mellitus

,

rheumatoid arthritis

,

atrial fibrillation

,

,

systemic scleroderma

,

juvenile arthritis

,

psoriatic arthritis

,

ankylosing spondylitis

,

sjogren's syndrome

,

undifferentiated connective tissue diseases

,

,

,

mixed connective tissue disease

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