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Day One Biopharmaceuticals
Day One Biopharmaceuticals
(DAWN)
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Clinical Trials
Therapeutic Areas:
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Drug Name
Phase 1
Phase 2
Phase 3
Phase 4
Indication
Tovorafenib
neoplasms
,
glioma
,
colorectal neoplasms
,
pancreatic neoplasms
,
non-small-cell lung carcinoma
,
melanoma
,
astrocytoma
,
mutation rate
,
carcinoma
,
urinary bladder neoplasms
,
adenocarcinoma
,
papillary thyroid cancer
,
acinar cell carcinoma
,
craniopharyngioma
,
brain neoplasms
,
diffuse intrinsic pontine glioma
Bevifimod
healthy volunteers/patients
,
knee osteoarthritis
,
osteoarthritis
,
hypoglycemia
,
brca1 genes
,
telomeric repeat binding protein 2
,
plexiform neurofibroma
,
neurofibromatoses
,
neurofibroma
,
coronary disease
,
coronary artery disease
,
myocardial ischemia
,
hypersensitivity
,
hematologic neoplasms
,
urologic neoplasms
,
uveal neoplasms
,
uveal melanoma
,
liver diseases
,
hepatic insufficiency
,
squamous cell carcinoma
,
rheumatoid arthritis
,
endometrial neoplasms
,
pancreatic neoplasms
,
fallopian tube neoplasms
,
neurofibromatosis 1
,
pancreatic ductal carcinoma
,
oropharyngeal neoplasms
,
squamous cell neoplasms
,
hereditary breast and ovarian cancer syndrome
,
type 1 diabetes mellitus
,
leukemia
,
lymphoid leukemia
,
hereditary sensory and autonomic neuropathies
,
melanoma
,
uterine neoplasms
,
adenocarcinoma of lung
,
waldenstrom macroglobulinemia
,
sarcoma
,
rectal neoplasms
,
esophageal squamous cell carcinoma
,
small cell carcinoma
,
mouth neoplasms
,
lip neoplasms
,
laryngeal neoplasms
,
serous cystadenocarcinoma
,
pain
,
diabetic neuropathies
,
b-cell lymphoma marginal zone
,
neurofibrosarcoma
,
chronic obstructive pulmonary disease
,
parkinson disease
,
urethral neoplasms
,
ureteral neoplasms
,
pelvic neoplasms
,
castration-resistant prostatic neoplasms
,
precursor cell lymphoblastic leukemia-lymphoma
,
nasopharyngeal carcinoma
,
nasopharyngeal neoplasms
,
epstein-barr virus infections
,
glioblastoma
,
glioma
,
peripheral nervous system diseases
,
neuritis
,
uterine cervical neoplasms
,
residual neoplasm
,
hodgkin disease
,
large-cell lymphoma anaplastic
,
t-cell lymphoma peripheral
,
pleural effusion
,
malignant pleural effusion
,
myocardial infarction
,
reperfusion injury
,
kidney neoplasms
,
renal cell carcinoma
,
colonic neoplasms
,
reactive arthritis
,
breast neoplasms
,
neoplasms
,
neoplasm metastasis
,
carcinoma
,
ovarian neoplasms
,
colorectal neoplasms
,
non-hodgkin lymphoma
,
hepatocellular carcinoma
,
adenocarcinoma
,
liver neoplasms
,
large b-cell lymphoma diffuse
,
stomach neoplasms
,
small cell lung carcinoma
,
lymphoma
,
squamous cell carcinoma of head and neck
,
recurrence
,
chronic renal insufficiency
,
biliary tract neoplasms
,
mantle-cell lymphoma
,
esophageal neoplasms
,
head and neck neoplasms
,
hyperkalemia
,
triple negative breast neoplasms
,
urinary bladder neoplasms
,
b-cell lymphoma
,
anemia
,
asthma
,
covid-19
,
multiple myeloma
,
breast diseases
,
mesothelioma
,
transitional cell carcinoma
,
cardiovascular diseases
,
chronic kidney failure
,
skin diseases
,
malignant mesothelioma
,
neoplasms by site
,
laryngeal diseases
,
communicable diseases
,
infectious skin diseases
,
hyperglycemia
,
weight loss
,
ovarian reserve
,
respiratory syncytial virus infections
,
crohn disease
,
inflammatory bowel diseases
,
pituitary dwarfism
,
hypopituitarism
,
dwarfism
,
gastrointestinal stromal tumors
,
lymphoproliferative disorders
,
unknown primary neoplasms
,
postpartum hemorrhage
,
acute coronary syndrome
,
syndrome
,
male breast neoplasms
,
non-small-cell lung carcinoma
,
type 2 diabetes mellitus
,
diabetes mellitus
,
lung neoplasms
,
prostatic neoplasms
,
b-cell chronic lymphocytic leukemia
,
obesity
,
insulin resistance
,
kidney diseases
,
ovarian epithelial carcinoma
,
b-cell leukemia
,
hypertension
,
infections
,
overweight
,
lymphatic diseases
,
heart failure
,
left ventricular dysfunction
,
ventricular dysfunction
,
fatty liver
,
otosclerosis
,
brain injuries
,
pneumonia
,
bacterial pneumonia
,
pancreatitis
,
inflammation
,
disease
,
diagnosis
,
smoking
,
family relations
,
amyloidosis
,
polyneuropathies
,
familial amyloid neuropathies
,
amyloid neuropathies
,
familial amyloidosis
,
respiratory syncytial viruses
PIMASERTIB
neoplasms
,
colorectal neoplasms
,
breast neoplasms
,
non-small-cell lung carcinoma
,
melanoma
,
neoplasm metastasis
,
ovarian neoplasms
,
ovarian epithelial carcinoma
Globulin, immune
brain neoplasms
,
respiratory tract diseases
,
respiration disorders
,
osteoporosis
,
male breast neoplasms
,
bites and stings
,
inflammatory bowel diseases
,
infections
,
hiv infections
,
acquired immunodeficiency syndrome
,
communicable diseases
,
bacillary dysentery
,
dysentery
,
drug-related side effects and adverse reactions
,
geographic atrophy
,
multiple sclerosis
,
relapsing-remitting multiple sclerosis
,
sclerosis
,
stroke
,
rectal neoplasms
,
atopic dermatitis
,
dermatitis
,
stomach neoplasms
,
gastrointestinal neoplasms
,
digestive system neoplasms
,
neoplasms by site
,
malaria
,
falciparum malaria
,
lymphoma
,
colorectal neoplasms
,
renal cell carcinoma
,
plasma cell neoplasms
,
diabetes mellitus
,
pancreatic neoplasms
,
follicular lymphoma
,
hepatocellular carcinoma
,
fallopian tube neoplasms
,
dengue
,
uterine cervical neoplasms
,
amyloidosis
,
non-small-cell lung carcinoma
,
melanoma
,
sjogren's syndrome
,
kidney transplantation
,
b-cell lymphoma
,
crohn disease
,
ulcerative colitis
,
waldenstrom macroglobulinemia
,
liver neoplasms
,
sarcoma
,
neoplasm metastasis
,
glioblastoma
,
malignant mesothelioma
,
cutaneous malignant melanoma
,
patient compliance
,
microsatellite repeats
,
macular degeneration
,
mantle-cell lymphoma
,
obesity
,
hypertension
,
pre-eclampsia
,
colitis
,
ulcer
,
mumps
,
measles
,
rubella
,
chickenpox
,
hodgkin disease
,
neonatal sepsis
,
membranous glomerulonephritis
,
nephrotic syndrome
,
endometrioid carcinoma
,
clear cell sarcoma
,
granulomatosis with polyangiitis
,
anti-neutrophil cytoplasmic antibody-associated vasculitis
,
peritoneal neoplasms
,
glioma
,
gliosarcoma
,
neuroendocrine carcinoma
,
adrenocortical carcinoma
,
clear cell adenocarcinoma
,
large cell carcinoma
,
vaginal neoplasms
,
vulvar neoplasms
,
graft rejection
,
breast neoplasms
,
neoplasms
,
non-hodgkin lymphoma
,
multiple myeloma
,
rheumatoid arthritis
,
b-cell chronic lymphocytic leukemia
,
ovarian neoplasms
,
leukemia
,
lymphoid leukemia
,
carcinoma
,
type 1 diabetes mellitus
,
autoimmune diseases
,
squamous cell carcinoma of head and neck
,
recurrence
,
head and neck neoplasms
,
endometrial neoplasms
,
lung neoplasms
,
postmenopausal osteoporosis
,
lung diseases
,
meningitis
,
meningococcal meningitis
,
adenocarcinoma
,
small cell lung carcinoma
,
inflammatory breast neoplasms
,
ductal carcinoma breast
,
squamous cell carcinoma
,
chronic obstructive pulmonary disease
,
papillomavirus infections
,
uterine cervical dysplasia
,
interstitial lung diseases
,
healthy volunteers/patients
,
bone fractures
,
large b-cell lymphoma diffuse
,
pemphigus
,
myocardial infarction
,
st elevation myocardial infarction
,
cervical intraepithelial neoplasia
,
streptococcal infections
,
hypereosinophilic syndrome
,
diffuse scleroderma
,
mucinous adenocarcinoma
,
anthrax
,
hemorrhage
,
thrombocytopenic purpura idiopathic
,
thrombocytopenia
,
microscopic polyangiitis
,
connective tissue diseases
,
hepatitis b
,
asthma
,
hepatitis
,
hepatitis a
,
arthritis
,
systemic lupus erythematosus
,
meningococcal infections
,
pulmonary eosinophilia
,
haemophilus influenzae type b
,
tetanus
,
diphtheria
,
virus diseases
,
covid-19
,
neisseria meningitidis
,
rabies
,
haemophilus infections
,
systemic scleroderma
,
psoriasis
,
psoriatic arthritis
,
rotavirus infections
,
human influenza
,
herpes zoster
,
juvenile arthritis
,
vasculitis
,
poliomyelitis
,
tetany
,
coronary artery bypass
,
eosinophilia
,
premature birth
,
vaccination
,
arteritis
,
giant cell arteritis
,
polymyalgia rheumatica
,
rheumatic diseases
,
spondylarthropathies
,
systemic vasculitis
,
collagen diseases
,
streptococcus agalactiae
,
pneumonia
,
pneumococcal pneumonia
,
pneumococcal infections
Histone-arginine methyltransferase carm1
hypogonadism
Surlorian
healthy volunteers/patients
,
squamous cell carcinoma of head and neck
,
squamous cell carcinoma
,
triple negative breast neoplasms
,
head and neck neoplasms
,
melanoma
,
parkinson disease
,
myeloid leukemia acute
,
carcinoma
,
large b-cell lymphoma diffuse
,
acute kidney injury
,
follicular lymphoma
,
liver cirrhosis
,
fibrosis
,
hepatitis c
,
chronic hepatitis c
,
hepacivirus
,
vascular surgical procedures
,
wounds and injuries
,
recurrence
,
non-hodgkin lymphoma
,
hairy cell leukemia
,
b-cell chronic lymphocytic leukemia
,
b-cell lymphoma marginal zone
,
pancreatic neoplasms
,
neoplasm metastasis
,
adenocarcinoma
,
urologic neoplasms
,
transitional cell carcinoma
,
ulcerative colitis
,
crohn disease
,
obesity
,
overweight
,
neoplasms
,
non-small-cell lung carcinoma
,
multiple myeloma
,
myelodysplastic syndromes
,
plasma cell neoplasms
,
ovarian neoplasms
,
hepatocellular carcinoma
,
liver neoplasms
,
takayasu arteritis
,
fallopian tube neoplasms
,
peritoneal neoplasms
,
psoriasis
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